发明名称 |
Gene encoding a protein and preventive/remedy for neurodegenerative diseases such as polyglutamine diseases by utilizing the same |
摘要 |
To provide a novel protein that can be a preventive/remedy in neurodegenerative diseases such as polyglutamine diseases based on the finding obtained by revealing the relationship between transcriptional dysfunction and neuronal death. Disclosed is a protein that is one of the following proteins (a) and (b). (a) A protein including an amino acid sequence represented by any one of SEQ ID NOS: 1 to 3. (b) A protein including an amino acid sequence in which one to several amino acids are deleted, substituted or added in the amino acid sequence of (a), the protein having a dominant negative effect on a transcriptional activation factor YAP.
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申请公布号 |
US7951928(B2) |
申请公布日期 |
2011.05.31 |
申请号 |
US20050791053 |
申请日期 |
2005.11.16 |
申请人 |
TOKYO MEDICAL AND DENTAL UNIVERSITY |
发明人 |
OKAZAWA HITOSHI |
分类号 |
C07H21/04;C12N5/02;C12N15/74;C12P21/06 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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