| 摘要 |
THE PRESENT INVENTION RELATES TO CERTAIN NOVEL COMPOUNDS OF THE FORMULA I TO PROCESSES FOR PREPARING SUCH COMPOUNDS, TO THEIR THE UTILITY IN MODULATION OF NUCLEAR HORMONE RECEPTORS LIVER X RECEPTOR (LXR) &Agr; (NR1H3) AND/OR &Bgr; (NR1H2) AND IN TREATING AND/OR PREVENTING CLINICAL CONDITIONS INCLUDING CARDIOVASCULAR DISEASES SUCH AS ATHEROSCLEROSIS; INFLAMMATORY DISEASES, ALZHEIMER’S DISEASE, LIPID DISORDERS (DYSLIPIDEMIAS) WHETHER OR NOT ASSOCIATED WITH INSULIN RESISTANCE, TYPE 2 DIABETES AND OTHER MANIFESTATIONS OF THE METABOLIC SYNDROME, TO METHODS FOR THEIR THERAPEUTIC USE AND TO PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
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