发明名称 [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE
摘要 The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.
申请公布号 KR20110057157(A) 申请公布日期 2011.05.31
申请号 KR20117005841 申请日期 2009.08.20
申请人 SANOFI-AVENTIS 发明人 CHOI SLEDESKI YONG MI;CHOI, NAK YEN;POLI GREGORY BERNARD;SHAY JOHN J. JR.;SHUM PATRICK WAI KWOK;SLEDESKI ADAM W.
分类号 C07D401/06;A61K31/454;A61P29/00 主分类号 C07D401/06
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