METHOD AND REAGENTS FOR TREATING HEPATIC FIBROSIS AND INFLAMMATION
摘要
<p>The invention relates to methods for identifying an anti-fibrotic or anti- inflammatory agent comprising determining cathepsin S expression in activated hepatic stellate cells which have been exposed to a test compound and comparing expression to non-exposed hepatic stellate cells. The invention also relates to methods for treating a disorder characterised or caused by hepatic fibrosis or inflammation, comprising administering a cathepsin S inhibitor to a subject.</p>