| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present invention refers to immunology and biotechnology. The method prevents immune cell attachment to the other cells involving contacting of the immune cells and other cells with a composition containing Bst2 antagonist. The antagonist is specified in a group: protein Bst2, fused protein on the based thereof or on the basis of its fragments with anti-inflammatory activity or aHTH-Bst2 antibodies. There are also described: a method of inflammation reduction in a subject and a method of treatment of a disease associated connected with the inflammation, mediated by Bst2 superexpression with the use of Bst2 antagonists. ^ EFFECT: inventions provide the use of Bst2 protein and its proper antagonists for prevention of adhesion of immune cells, as well as said cells and immune system cells that can find further application in medicine in treating inflammatory diseases. ^ 12 cl, 39 dwg, 42 ex |
