发明名称 STABLE COCRYSTALS OF TEMOZOLOMIDE
摘要 <p>Disclosed herein are novel pharmaceutical cocrystals of temozolomide using co-crystal coformers selected from aliphatic and aromatic carboxylic acids in fixed stoichiometric ratio. The novel Temozolomide-carboxylic acid cocrystals exhibit improved hydrolytic stability and good aqueous dissolution rate compared to the pure drug.</p>
申请公布号 WO2011036676(A8) 申请公布日期 2011.05.26
申请号 WO2010IN00613 申请日期 2010.09.14
申请人 NANGIA, ASHWINI;NANUBOLU, JAGADEESH, BABU;SANPHUI, PALASH 发明人 NANGIA, ASHWINI;NANUBOLU, JAGADEESH, BABU;SANPHUI, PALASH
分类号 A61K31/4188 主分类号 A61K31/4188
代理机构 代理人
主权项
地址