发明名称 AGENT HAVING ANGIOTENSIN CONVERTING ENZYME-INHIBITORY ACTIVITY AND HYPOTENSIVE EFFECT, AND METHOD FOR PRODUCING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide an agent that contains a peptide such as a non-biodegradable peptide having minimized in vivo zymolytic activity, and free amino acids, and exhibits ACE inhibitory activity or a hypotensive effect and a method for producing the same. <P>SOLUTION: The agent includes as an effective ingredient a casein hydrolyzate containing free amino acids obtained by hydrolyzing animal milk casein into an average chain length of 2.1 or less in terms of the number of amino acid residues by a specific process, and a non-biodegradable peptide such as Xaa Pro and Xaa Pro Pro in a specific ratio, and is a useful agent exhibiting ACE inhibitory activity and a hypotensive effect. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011102327(A) 申请公布日期 2011.05.26
申请号 JP20110031140 申请日期 2011.02.16
申请人 CALPIS CO LTD 发明人 YAMAMOTO NAOYUKI;MIZUNO SEIICHI;NISHIMURA SHINGO;GOTO TAKANOBU;MATSUURA KEIICHI;SHINODA SUNAO
分类号 A61K38/00;A23L1/305;A61K38/01;A61K38/55;A61P9/12;A61P43/00;C07K5/06;C07K5/062;C07K5/068;C07K5/072;C07K5/083;C07K7/14;C12P21/06 主分类号 A61K38/00
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