发明名称 |
ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF |
摘要 |
Disclosed is an isolated antigen binding proteins, such as but not limited to, an antibody or antibody fragment, that specifically bind to SEQ ID NO:4, the amino acid sequence of extracellular loop 2 (ECL2) of human Orai1. Also disclosed are pharmaceutical compositions and medicaments comprising the antigen binding protein, isolated nucleic acid encoding it, vectors and host cells useful in methods of making it, and methods of using it in treating disorders or diseases in patients. |
申请公布号 |
CA2781532(A1) |
申请公布日期 |
2011.05.26 |
申请号 |
CA20102781532 |
申请日期 |
2010.11.19 |
申请人 |
AMGEN INC. |
发明人 |
NGUYEN, HUNG Q.;LIN, FEN-FEN;BI, XIAO-JUAN;MCBRIDGE, HELEN J.;HU, SYLVIA SHAW-FEN |
分类号 |
A61K39/395;A61P37/06;C07K14/705;C07K16/28;C07K19/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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