| 发明名称 |
Optimized Anti-CD30 Antibodies |
| 摘要 |
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody. |
| 申请公布号 |
AU2011202115(A1) |
申请公布日期 |
2011.05.26 |
| 申请号 |
AU20110202115 |
申请日期 |
2011.05.09 |
| 申请人 |
XENCOR, INC. |
发明人 |
GREGORY ALAN LAZAR;JOHN R. DESJARLAIS;PHILIP W. HAMMOND;DAVID F. CARMICHAEL;BAO-LU CHEN;SEUNG Y. CHU;SHER BAHADUR KARKI |
| 分类号 |
C07K16/28;A61K39/395;A61P35/02 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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