发明名称 N-BENZYL AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a compound useful as a therapeutic agent for pain and inflammation caused by various diseases, such as neurogenic pain and rheumatoid arthritis. SOLUTION: The compound is an N-benzyl amide derivative represented by formula (I) [wherein R<SP>1</SP>is methoxy, OH or H; R<SP>2</SP>is H, alkyl, alkylcarbonyl or arylcarbonyl; and D is represented by formula (A)-(C) äwherein R<SP>3</SP>is a hydrocarbon group chosen from the group consisting of alkyl, alkenyl, alkynyl and alkenylalkynyl, provided that the group is optionally substituted 3-8C cycloalkyl or optionally substituted aryl}] or a physiologically acceptable salt thereof. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011102266(A) 申请公布日期 2011.05.26
申请号 JP20090257819 申请日期 2009.11.11
申请人 DAINIPPON SUMITOMO PHARMA CO LTD 发明人 MORIE TOSHIYA;ADACHI KEIJI
分类号 C07C233/60;A61K31/165;A61P1/00;A61P1/04;A61P3/04;A61P3/10;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P13/10;A61P17/00;A61P17/04;A61P19/02;A61P25/04;A61P25/06;A61P29/00;A61P37/08;A61P43/00 主分类号 C07C233/60
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