发明名称 |
GENE INVOLVED IN THE BIOSYNTHESES OF LYCOPENE, RECOMBINANT VECTOR COMPRISING THE GENE, AND TRANSFORMED MICROORGANISM WITH THE RECOMBINANT VECTOR |
摘要 |
There are provided genes involved in the biosynthesis of lycopene and having DNA sequences set forth in SEQ ID NO: 1, SEQ ID NO: 3 and SEQ ID NO: 5 encoding proteins required for the biosynthesis of lycopene, a recombinant vector comprising at least one of the genes, and a mi croorganism transformed with the recombinant vector and having a high content of lycopene. The lycopene is obtained at a yield of 15.3 mg/L and a content of 4.2 mg/gDCW when the recombined E. coli with the crt genes is cultivated, and the lycopene is also obtained with the maximum content of 5.4 mg/gDCW when a microorganism is transformed with the combination of the gene of the present invention and the known genes. Therefore, provided is the lycopene-producing strain having a more increased content of lycopene per dry cell weight than the known lycopene-producing strain with the genes. Accordingly, the genes may be useful to mass-produce lycopene in microorganisms, and also to mass-produce carotenoids.
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申请公布号 |
US2011124090(A1) |
申请公布日期 |
2011.05.26 |
申请号 |
US20080594659 |
申请日期 |
2008.04.07 |
申请人 |
SK ENERGY CO., LTD.;AMICOGEN CO., LTD. |
发明人 |
CHO NAHM RYUNE;PARK MIN SOO;LEE DONG HYUN;CHUNG HO SEUNG;KIM JONG KEUN |
分类号 |
C12N1/21;C07H21/04;C12N15/70 |
主分类号 |
C12N1/21 |
代理机构 |
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