发明名称 INDUCER OF SELECTIVE DIFFERENTIATION INTO NEURAL STEM CELLS AND/OR NEURAL PRECURSOR CELLS
摘要 Disclosed are: a differentiation inducer which is capable of selectively inducing the differentiation of stem cells into neural stem cells and/or neural precursor cells; and a method for inducing the differentiation of stem cells into neural stem cells and/or neural precursor cells. Specifically disclosed is a differentiation inducer which contains a compound represented by general formula (I). (In the formula, R1 represents an oxygen atom, H2, or a C1-C9 alkyl group which is substituted by a phenyl group; R2 represents a hydrogen atom, -OH, or a C1-C9 alkyl group, alkenyl group or alkynyl group; R3 and R4 combine together to form a cyclic alkyl or a cyclic alkenyl, or alternatively R3 and R4 each independently represents a hydrogen atom, -O, or a C1-C9 alkyl group, alkenyl group or alkynyl group; and R5 and R6 combine together to form a cyclic alkyl or a cyclic alkenyl, or alternatively R5 and R6 each independently represents a hydrogen atom or a C1-C9 alkyl group. In this connection, the cyclic alkyl, the cyclic alkenyl, the alkyl group, the alkenyl group or the alkynyl group may be independently substituted by one or more substituents that are selected from among a hydrogen atom, -OH, an aliphatic ester, an aliphatic dicarboxylic acid ester and a halogen.)
申请公布号 WO2011062013(A1) 申请公布日期 2011.05.26
申请号 WO2010JP67930 申请日期 2010.10.13
申请人 THE UNIVERSITY OF TOKUSHIMA;ITOH, KOHJI;TSUJI, DAISUKE;TAKAISHI, YOSHIHISA;KASHIWADA, YOSHIKI 发明人 ITOH, KOHJI;TSUJI, DAISUKE;TAKAISHI, YOSHIHISA;KASHIWADA, YOSHIKI
分类号 C12N5/0797;A61K35/30;A61P43/00;C12N5/0789;C12Q1/02;G01N33/15;G01N33/50 主分类号 C12N5/0797
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