METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
摘要
Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
申请公布号
WO2011063283(A2)
申请公布日期
2011.05.26
申请号
WO2010US57503
申请日期
2010.11.19
申请人
OREGON HEALTH & SCIENCE UNIVERSITY;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS;LEWINSOHN, DAVID, M.;LEWINSOHN, DEBORAH, A.