| 发明名称 |
Solid Forms of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-yl)-2-Trifluoromethyl)Phenyl)-4-Oxo-5-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxamide |
| 摘要 |
The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith.
|
| 申请公布号 |
US2011123449(A1) |
申请公布日期 |
2011.05.26 |
| 申请号 |
US20100909789 |
申请日期 |
2010.10.21 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
ZHANG BEILI;KRAWIEC MARIUSZ;LUISI BRIAN;MEDEK ALES |
| 分类号 |
A61K49/00;A61K31/4709;A61P1/00;A61P3/00;A61P11/00;A61P19/02;A61P25/00;C07D401/14;C12Q1/02 |
主分类号 |
A61K49/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
