摘要 |
<p>Provided are compounds which generally have a triketone structure. Examples of the compounds include derivatives of 1,3-cyclohexanedione, such as: 1,3-cyclohexanedione, 2-propanoyl-5-cyclohexyl-; 1,3-cyclohexanedione, 2-propanoyl-5-[4-fluorophenyl]-; 1,3-cyclohexanedione, 2-acetyl-5-[thien-2-yl]-; 1,3-cyclohexanedione, 2-acetyl-5 -butyl-; and 1,3-cyclohexanedione, 2-propanoyl-5-[bicyclo[2.2.1]hept-2-en-5-yl]-. The compounds can be used to alter the lifespan of eukaryotic organisms and treat inflammation.</p> |
申请人 |
UNIVERSITY OF ROCHESTER;SOUTHERN RESEARCH INSTITUTE;GOLDFARB, DAVID, S.;MADDRY, JOSEPH, A.;RASMUSSEN, LYNN;WHITE, ELLIE, LUCILE;WENNERBERG, KRISTER |
发明人 |
GOLDFARB, DAVID, S.;MADDRY, JOSEPH, A.;RASMUSSEN, LYNN;WHITE, ELLIE, LUCILE;WENNERBERG, KRISTER |