发明名称 ARGININE-BASED AMPHIPHILIC PEPTIDE MICELLE
摘要 The present invention provides a peptide micelle formed from a peptide comprising a certain number of arginines and hydrophobic amino acids. In addition, the present invention provides a drug delivery vehicle comprising the peptide micelle of the present invention, and a nucleic acid hybrid composite further comprising hybrid nucleic acids. Since the peptide micelle comprising an arginine-based short peptide according to the present invention shows low toxicity and has nucleic acid transfer efficiency higher than or similar to that of polymer vectors of which the use had been considered in the prior art, the peptide micelle is useful as a safer nucleic acid therapeutic agent.
申请公布号 WO2011002258(A3) 申请公布日期 2011.05.26
申请号 WO2010KR04310 申请日期 2010.07.02
申请人 INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY;LEE, MIN-HYUNG;KIM, HYUN-AH;RYU, DONG-WOOK;PARK, JI-HWAN;LEE, JI-YOUNG;HYUN, HYE-SUN 发明人 LEE, MIN-HYUNG;KIM, HYUN-AH;RYU, DONG-WOOK;PARK, JI-HWAN;LEE, JI-YOUNG;HYUN, HYE-SUN
分类号 A61K9/127;A61K9/38;A61K31/195;A61K31/198 主分类号 A61K9/127
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