COMBINATIONS COMPRISING A GLUCOCORTICOID RECEPTOR MODULATOR FOR THE TREATMENT OF RESPIRATORY DISEASES

摘要

The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is a glucocorticoid receptor modulator and a second active ingredient selected from an Adenosine A2A receptor antagonist, an anti-infective, an antioxidant, a ß2 adrenoceptor agonist, a CCR1 antagonist, a chemokine antagonist, a muscarinic antagonist, a glucocorticosteroid, a CRTh2 antagonist, a DP1 antagonist, a formyl peptide receptor antagonist, a Histone Deacetylase activator, a chloride channel hCLCA1 blocker, an Epithelial sodium channel blocker, an Inter-cellular adhesion molecule 1 blocker, an IKK2 kinase inhibitor, a JNK kinase inhibitor, a COX inhibitor, a lipoxygenase inhibitor, a leukotriene receptor antagonist, a MEK-1 kinase inhibitor, a MPO inhibitor, a PDE4, inhibitor, a PI 3 kinase ? inhibitor, a PPAR? agonist, a protease inhibitor, a p38 inhibitor, a RAR? modulator, a statin, a thromboxane antagonist and a vasodilator; and its use in the treatment of respiratory disease.