| 发明名称 |
Antiviral Oligonucleotides Having a Conserved G4 Core Sequence |
| 摘要 |
Modified oligonucleotides having a conserved G4 sequence and a sufficient number of flanking nucleotides to significantly inhibit the activity of a virus are provided. G4 quartet oligonucleotide structures are also provided. Methods of prophylaxis, diagnostics and therapeutics for viral-associated diseases are also provided.
|
| 申请公布号 |
US2011124715(A1) |
申请公布日期 |
2011.05.26 |
| 申请号 |
US20100849886 |
申请日期 |
2010.08.04 |
| 申请人 |
HANECAK RONNIE C;ANDERSON KEVIN P;BENNETT C FRANK;CHIANG MING-YI;BROWN-DRIVER VICKIE L;ECKER DAVID J;VICKERS TIMOTHY;WYATT JACQUELINE R |
发明人 |
HANECAK RONNIE C.;ANDERSON KEVIN P.;BENNETT C. FRANK;CHIANG MING-YI;BROWN-DRIVER VICKIE L.;ECKER DAVID J.;VICKERS TIMOTHY;WYATT JACQUELINE R. |
| 分类号 |
A61K31/7088;C12N15/09;A01N63/00;A61K31/70;A61K38/00;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P35/00;C07H21/00;C07H21/04;C12N7/00;C12N15/113;C12N15/115;C12N15/117;C12P19/34;C12Q1/68;C12Q1/70 |
主分类号 |
A61K31/7088 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
