发明名称 |
3,4-di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
摘要 |
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
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申请公布号 |
US7947720(B2) |
申请公布日期 |
2011.05.24 |
申请号 |
US20090352781 |
申请日期 |
2009.01.13 |
申请人 |
SCHERING CORPORATION;PHARMACOPEIA DRUG DISCOVERY |
发明人 |
TAVERAS ARTHUR G.;AKI CYNTHIA J.;BOND RICHARD W.;CHAO JIANPING;DWYER MICHAEL;FERREIRA JOHAN A.;CHAO JIANHUA;YU YOUNONG;BALDWIN JOHN J.;KAISER BERND;LI GE;MERRITT J. ROBERT;BIJU PURAKKATTLE J.;NELSON, JR. KINGSLEY H.;ROKOSZ LAURA L. |
分类号 |
C07D261/04;A01N43/06;A01N43/80;A61K31/166;A61K31/18;A61K31/341;A61K31/343;A61K31/357;A61K31/381;A61K31/40;A61K31/4025;A61K31/422;A61K31/472;A61K31/506;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P11/14;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P19/02;A61P19/06;A61P19/10;A61P25/00;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/14;A61P31/18;A61P33/06;A61P35/00;A61P37/06;C07C225/20;C07C237/30;C07C237/36;C07C237/44;C07C255/59;C07C311/39;C07D207/32;C07D207/335;C07D213/74;C07D217/24;C07D295/26;C07D307/38;C07D307/52;C07D307/56;C07D307/68;C07D307/79;C07D307/81;C07D307/82;C07D307/83;C07D317/46;C07D319/18;C07D327/04;C07D333/20;C07D333/36;C07D333/40;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D413/14 |
主分类号 |
C07D261/04 |
代理机构 |
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地址 |
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