| 发明名称 |
Compositions and methods for regulating mRNA transcription and translation |
| 摘要 |
The invention relates to compositions, specifically novel nucleic acid constructs encoding a cardiovirus 2A polypeptide operably linked to suitable promoters. Also, disclosed are methods whereby the nucleic acid constructs are introduced into cells or cell free systems to regulate cellular mRNA transcription and cap-dependent or internal ribosomal entry site (IRES)-dependent mRNA translation.
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| 申请公布号 |
US7947493(B2) |
申请公布日期 |
2011.05.24 |
| 申请号 |
US20040888143 |
申请日期 |
2004.07.09 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
PALMENBERG ANN C.;AMINEV ALEKSEY G.;GROPPO RACHEL P. |
| 分类号 |
C12N15/00;C07K14/085;C12N15/10;C12N15/11;C12N15/34;C12N15/67 |
主分类号 |
C12N15/00 |
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