发明名称 |
METHOD AND APPARATUS FOR PREPARING PARTICLES |
摘要 |
Method for Preparing a target substance in particulate form, comprising introducing into a particle formation vessel, through separate first and second fluid inlet means respectively, (a) a "target solution/suspension" of the substance in a fluid vehicle and (b) a compressed fluid anti-solvent, and allowing the anti-solvent to extract the vehicle so as to form particles of the substance, wherein the anti-solvent fluid has a sonic, near-sonic or supersonic velocity as it enters the vessel, and wherein the anti-solvent and the target solution/suspension enter the vessel at different locations and meet downstream (in the direction of anti-solvent flow) of the second fluid inlet means. Also provided is apparatus for use in such a method.
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申请公布号 |
CA2454331(C) |
申请公布日期 |
2011.05.24 |
申请号 |
CA20022454331 |
申请日期 |
2002.07.17 |
申请人 |
NEKTAR THERAPEUTICS UK LTD. |
发明人 |
KORDIKOWSKI, ANDREAS;PALAKODATY, SRINIVAS;GILBERT, DARREN JOHN |
分类号 |
A61J3/06;B01J2/04;A61K9/00;A61K9/16;A61K9/50;B01F5/02;B01J2/06;B01J3/00 |
主分类号 |
A61J3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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