The present invention provides methods to produce pluripotent stem cells from adult cells. In particular, the present invention provides methods to produce pluripotent stem cells from somatic cells without the use of a feeder-cell layer or an agent that increases efficiency of retroviral transfection.
申请公布号
WO2011059725(A2)
申请公布日期
2011.05.19
申请号
WO2010US54408
申请日期
2010.10.28
申请人
CENTOCOR ORTHO BIOTECH INC.;FUNG, RAMIE;FRYER, BENJAMIN