发明名称 HETEROCYCLIC DERIVATIVES THAT ARE USED IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
摘要 The present invention relates to compounds of Formula (I) below, to their pharmaceutically acceptable salts and to their isomers or mixtures of isomers: HetAr—X—CHR1R2 (I) in which: -HetAr represents a group chosen from: —X represents a linear, saturated or unsaturated, hydrocarbon-based chain comprising from 8 to 22 carbon atoms, optionally interrupted by an —NH— or —NH—CO— group, —R1 represents a hydrogen atom or an —OH, —O(C1-C6)alkyl, —OCO((C1-C6)alkyl), —OSO2((C1-C6)alkyl) or —OSO3H group, and —R2 represents a hydrogen atom or a (C2-C6)alkynyl, (C2-C6)alkenyl or (C3-C6)cycloalkyl group. The present invention also relates to a process for preparing the compounds of Formula (I), and also to the use thereof, especially in the treatment of neurodegenerative diseases.
申请公布号 US2011118270(A1) 申请公布日期 2011.05.19
申请号 US200913003992 申请日期 2009.07.20
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) 发明人 SCHMIDT FANNY
分类号 A61K31/498;A61K31/47;A61P25/28;C07D215/14;C07D241/42 主分类号 A61K31/498
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