| 发明名称 |
CATIONIC SIRNAS, SYNTHESIS AND USE FOR RNA INTERFERENCE |
| 摘要 |
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.
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| 申请公布号 |
US2011118331(A1) |
申请公布日期 |
2011.05.19 |
| 申请号 |
US20090735595 |
申请日期 |
2009.01.30 |
| 申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
BEHR FRANCE JEAN-PAUL;KOTERA MITSUHARU;PFENDER NADEGE;REMY JEAN-SERGE |
| 分类号 |
C07H21/02;A61K31/7105;C12N15/11 |
主分类号 |
C07H21/02 |
| 代理机构 |
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