Variant immunoglobulins with one or more amino acid modifications in the Fc region that have increased in vivo half-lives, and methods of using the same are provided.
申请公布号
MX2011004001(A)
申请公布日期
2011.05.19
申请号
MX20110004001
申请日期
2009.10.13
申请人
GENENTECH, INC.
发明人
FERRARA, NAPOLEONE;MENG, YU-JU, G.;LOWMAN, HENRY, B.;DAMICO, LISA A.;YEUNG, YIK ANDY