NON-SPECTROSCOPIC LABEL-INDEPENDENT OPTICAL READER SYSTEM AND METHODS

摘要

A non-spectroscopic, label-independent optical reader system is disclosed, where an exemplary system includes a broadband light source that generates broadband light made incident upon the resonant waveguide grating (RWG) biosensor. The light reflects from the RWG biosensor to form biosensor-reflected light. A photodetector receives the reflected light and generates a first detector signal representative of the reflected light intensity. An optical-edge filter can filter the broadband light, the reflected light, or both. A processor calculates a resonant wavelength for the RWG biosensor based on the detector signal.