摘要 |
PROBLEM TO BE SOLVED: To provide a novel synthetic intermediate which can easily and inexpensively produce a nitrone compound having excellent properties as a spin trapping agent in a good yield and a process for producing the same. SOLUTION: A novel pyrrolidine compound, above all, 1-hydroxy-2-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-2-methylpyrrolidine (CYPMPOH) excels in stability and can be easily led to a nitrone compound by oxidation reaction. COPYRIGHT: (C)2011,JPO&INPIT
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