发明名称 COMPETITIVE INHIBITORS OF INVARIANT CHAIN EXPRESSION AND/OR ECTOPIC CLIP BINDING
摘要 The invention relates to methods for modulating the immune function through targeting of CLIP molecules. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including autoimmune disease, cancer, Alzheimer's disease, allergic disease, transplant and cell graft rejection, HIV infection and other viral, bacterial, and parasitic infection, and AIDS. Methods are also provided for preparing a peptide having the property of being able to displace CLIP by feeding one or more peptide sequences into software that predicts MHC Class II binding regions in an antigen sequence and related products.
申请公布号 US2011118175(A1) 申请公布日期 2011.05.19
申请号 US20080739459 申请日期 2008.10.23
申请人 REGENTS OF THE UNIVERSITY OF COLORADO 发明人 NEWELL MARTHA KAREN;NEWELL EVAN
分类号 A61K38/10;A61K38/08;A61P31/12;A61P33/00;C07K7/06;C07K7/08 主分类号 A61K38/10
代理机构 代理人
主权项
地址