NITROBENZENE DERIVATIVE, HIGHLY-REACTIVE-ROS-GENERATING AGENT USING SAME, AND METHOD FOR GENERATING HIGHLY-REACTIVE ROS
摘要
<p>Disclosed is a nitrobenzene derivative wherein the generation of peroxynitrite (ONOO-) can be controlled positionally and temporally by means of ultraviolet irradiation. Further disclosed is a highly-reactive-ROS-generating agent using same, and a method for generating a highly-reactive ROS. The nitrobenzene derivative is represented by the belowmentioned structural formula. This compound can generate NO radicals by means of light irradiation, and furthermore has a substituent group introduced that has the ability to generate superoxide anions (O2 -), and thus can generate peroxynitrite (ONOO-).</p>
申请公布号
WO2011058905(A1)
申请公布日期
2011.05.19
申请号
WO2010JP69473
申请日期
2010.11.02
申请人
NAGOYA CITY UNIVERSITY;NAKAGAWA, HIDEHIKO;IEDA, NAOYA;TSUMOTO, HIROKI;SUZUKI, TAKAYOSHI;MIYATA, NAOKI