发明名称 NITROBENZENE DERIVATIVE, HIGHLY-REACTIVE-ROS-GENERATING AGENT USING SAME, AND METHOD FOR GENERATING HIGHLY-REACTIVE ROS
摘要 <p>Disclosed is a nitrobenzene derivative wherein the generation of peroxynitrite (ONOO-) can be controlled positionally and temporally by means of ultraviolet irradiation. Further disclosed is a highly-reactive-ROS-generating agent using same, and a method for generating a highly-reactive ROS. The nitrobenzene derivative is represented by the belowmentioned structural formula. This compound can generate NO radicals by means of light irradiation, and furthermore has a substituent group introduced that has the ability to generate superoxide anions (O2 -), and thus can generate peroxynitrite (ONOO-).</p>
申请公布号 WO2011058905(A1) 申请公布日期 2011.05.19
申请号 WO2010JP69473 申请日期 2010.11.02
申请人 NAGOYA CITY UNIVERSITY;NAKAGAWA, HIDEHIKO;IEDA, NAOYA;TSUMOTO, HIROKI;SUZUKI, TAKAYOSHI;MIYATA, NAOKI 发明人 NAKAGAWA, HIDEHIKO;IEDA, NAOYA;TSUMOTO, HIROKI;SUZUKI, TAKAYOSHI;MIYATA, NAOKI
分类号 C07C205/20;A61K31/04;A61P35/00 主分类号 C07C205/20
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