Pharmaceutical compositions comprising an LRP1 receptor agonist for the treatment of cancer and HIV
摘要
The present invention provides a pharmaceutical composition comprising an LRP1 receptor agonist for use in the treatment of cancer characterized by an up-regulated or constitutively active Wnt signaling pathway and a method for identifying LRP1 receptor agonists suitable as therapeutic agents for treating such cancers. The present invention also provides a pharmaceutical composition comprising an LRP1 receptor agonist for use in the treatment of an HIV-infection. Furthermore, the present invention relates to the therapeutic use of LRP1 receptor agonists and a kit of parts comprising the pharmaceutical composition according to the invention.
申请公布号
EP2322204(A1)
申请公布日期
2011.05.18
申请号
EP20090176204
申请日期
2009.11.17
申请人
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITAET LEIPZIG
发明人
BIRKENMEIER, GERD;SCHAEFER, ANGELIKA;HEMDAN, NASR;BUCHOLD, MARTIN;LINDNER, INGE;BIGL, MARINA;GERDES, WILHELM