| 发明名称 |
AAV vectors for in vivo gene therapy of rheumatoid arthritis |
| 摘要 |
<p>The present invention relates to the field of adeno-associated virus (AAV) based gene therapy, in particular in vivo gene therapy, of rheumatoid arthritis (RA). The invention provides recombinant AAV virions being highly efficient in delivering genes encoding therapeutic proteins to the arthritic joints, and methods for using such virions in in vivo gene therapy.</p> |
| 申请公布号 |
EP2322638(A1) |
申请公布日期 |
2011.05.18 |
| 申请号 |
EP20100175639 |
申请日期 |
2004.09.01 |
| 申请人 |
ACADEMISCH MEDISCH CENTRUM;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
TAK, PAUL PETER;JORGENSEN, CHRISTIAN |
| 分类号 |
C12N15/861;A61K48/00;A61P19/02;C12N15/864 |
主分类号 |
C12N15/861 |
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