发明名称 |
CELL LINE, SYSTEM AND METHOD FOR OPTICAL CONTROL OF SECONDARY MESSENGERS |
摘要 |
A variety of methods, devices and compositions are implemented for light- activated molecules. One such method is implemented for generating secondary messengers in a cell. A nucleotide sequence for expressing a chimeric light responsive membrane protein (e.g., rhodopsin) is modified with one or more heterologous receptor subunits {e.g., an adrenergic receptor (alpha1, Beta2)}. The light responsive membrane protein is expressed in a cell for producing a secondary messenger in response to light. |
申请公布号 |
EP2294208(A4) |
申请公布日期 |
2011.05.18 |
申请号 |
EP20090759107 |
申请日期 |
2009.05.29 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
AIRAN, RAAG, D.;DEISSEROTH, KARL |
分类号 |
C12P21/06;C12P21/04 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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