发明名称 |
METHOD FOR THE ENHANCEMENT OF CHEMICAL SENSITIVITY OR RADIOSENSITIVITY OF CANCER CELLS BY INHIBITING THE EXPRESSION OF TSPYL 5 |
摘要 |
PURPOSE: A method for enhancing sensitivity of cancer cells with respect to compounds or radiation is provided to suppress cancer cell proliferation and to ensure sensitivity. CONSTITUTION: An anticancer adjuvant contains an inhibitor of TSPLY 5 protein having an amino acid of sequence number 1. The TSPLY 5 expression inhibitor is antisense nucleotide or small interfering RNA. The compound is cisplatin, methyl methane-sufonate(MMS), or hydrogen peroxide(H_2O_2).
|
申请公布号 |
KR20110052184(A) |
申请公布日期 |
2011.05.18 |
申请号 |
KR20090109125 |
申请日期 |
2009.11.12 |
申请人 |
KOREA ATOMIC ENERGY RESEARCH INSTITUTE |
发明人 |
KIM, IN GYU;KIM, KUG CHAN;LEE, SO YONG;KIM, TAE RIM;KIM, EUN JIN;JUNG, IL LAE |
分类号 |
A61K31/7105;A61K39/395;A61P35/00;C12N15/11 |
主分类号 |
A61K31/7105 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|