发明名称 |
VITAMIN D DERIVATIVES |
摘要 |
The object of the present invention is to provide vitamin D derivatives that have excellent physiological activities as medicines, particularly as therapeutic agents for skin diseases such as psoriasis, and that have a reduced hypercalcemic effect. The present invention provides a vitamin D derivative of Formula (1): (see formula 1) wherein X represents an oxygen atom or a sulfur atom; m represents a number of 1 to 3; R1 and R2 each represent a hydrogen atom or an alkyl group; R4 and R5 each represent a hydrogen atom or a hydroxyl group, etc.; R3 represents -YR8, etc.; R6 represents a hydrogen atom, etc.; and R7 represents a hydrogen atom, etc. |
申请公布号 |
CA2411409(C) |
申请公布日期 |
2011.05.17 |
申请号 |
CA20012411409 |
申请日期 |
2001.06.14 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
MORIKAWA, KAZUMI;OHMORI, MASAYUKI;SHIMIZU, KAZUKI;KAWASE, AKIRA;EMURA, TAKASHI |
分类号 |
C07C401/00;C07J5/00;A61K31/592;A61K31/593;A61P3/02;A61P17/00;C07B61/00;C07C235/06;C07D295/185;C07F7/18;C07J1/00;C07J7/00;C07J9/00 |
主分类号 |
C07C401/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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