摘要 |
The present invention relates to an apparatus and a method for sealing a puncture in a tubular tissue structure or the wall of a body cavity. More specifically, the present invention is directed to an apparatus and method for sealing a puncture site in the wall of a tubular tissue structure, or in the wall of a body cavity with submucosal tissue or another extracellular or matrix-derived tissue capable of remodeling endogenous connective tissue in vivo. The submucosal tissue or another extracellular or matrix-derived tissue is inserted into the puncture site as a sheet (Fig. 1:18) on an introducer element such as a needle (Fig. 1, 17), a cannula (Fig. 1:44), a guide wire (not shown), an introducer element adapted for dialysis (Fig. 1:10), an introducer element adapted for catherization (Fig. 1:10), a trocar (Fig. 1:16), or any other introducer element (Fig. 1:17) used to access the lumen of a tubular tissue structure or used to access a body cavity (Fig. 10A:78). |