| 发明名称 |
MALONAMIDE DERIVATIVES AS GAMMA-SECRETASE INHIBITORS |
| 摘要 |
The invention relates to malonamide derivatives of formula (IA) or (IB) and to pharmaceutically suitable acid addition salts thereof. The compounds are .gamma.-secretase inhibitors and the related compounds may be useful in the treatment of Alzheimer's disease.
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| 申请公布号 |
CA2514267(C) |
申请公布日期 |
2011.05.17 |
| 申请号 |
CA20042514267 |
申请日期 |
2004.01.27 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
GALLEY, GUIDO;GOERGLER, ANNICK;JACOBSEN, HELMUT;KITAS, ERIC ARGIRIOS;PETERS, JENS-UWE |
| 分类号 |
C07D223/18;A61K31/55;A61K31/5513;A61P25/28;C07C237/12;C07C237/14;C07D209/18;C07D209/44;C07D215/22;C07D215/227;C07D217/06;C07D243/12;C07D243/14;C07D243/24;C07D265/30;C07D401/04;C07D401/06;C07D401/12;C07D403/06;C07D405/12;C07D409/12;C07D471/04;C07D471/06;C07D471/08;C07D487/06 |
主分类号 |
C07D223/18 |
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