发明名称 Methods and compositions relating to CCR5 antagonist, IFN-γand IL-13 induced inflammation
摘要 The present invention includes compositions and methods for the treatment of Th1 and/or Th2 medicated inflammatory diseases, relating to inhibiting CCR5. This is because the present invention demonstrates, for the first time, that expression of IFN-γ, IL-13, and CCR5 mediates and/or is associated with Th1 and/or Th2 inflammatory diseases and that inhibiting CCR5 treats, and even prevents, the diseases. Thus, the Invention relates to the novel discovery that inhibiting CCR5 treats and prevents Th1 and/or Th2 mediated inflammatory disease.
申请公布号 US7943130(B2) 申请公布日期 2011.05.17
申请号 US20040582610 申请日期 2004.12.13
申请人 YALE UNIVERSITY 发明人 MA BING;ELIAS JACK A.
分类号 A61K39/395;A61K;C07K16/28 主分类号 A61K39/395
代理机构 代理人
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