2-PYRIDONE DERIVATIVES AS NEUTROPHIL ELASTASE INHIBITORS AND THEIR USE

摘要

THERE ARE PROVIDED NOVEL COMPOUNDS OF FORMULA (1)WHEREIN R1, R2, R4, R5, G1, G2, L, Y AND n ARE AS DEFINED IN THE SPECIFICATION AND OPTICAL ISOMERS, RACEMATES AND TAUTOMERS THEREOF, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF; TOGETHER WITH PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. THE COMPOUNDS ARE INHIBITORS OF NEUTROPHIL ELASTASE.