METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATMENT AND PROPHYLAXIS IN THE RESPIRATORY TRACT
摘要
The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.
申请公布号
WO2011057081(A1)
申请公布日期
2011.05.12
申请号
WO2010US55636
申请日期
2010.11.05
申请人
NEXBIO, INC.;FANG, FANG;WURTMAN, DAVID;MOSS, RON;MALAKHOV, MICHAEL
发明人
FANG, FANG;WURTMAN, DAVID;MOSS, RON;MALAKHOV, MICHAEL