发明名称 |
SPIRO-OXINDOLE MDM2 ANTAGONISTS |
摘要 |
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
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申请公布号 |
US2011112052(A1) |
申请公布日期 |
2011.05.12 |
申请号 |
US20100945511 |
申请日期 |
2010.11.12 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WANG SHAOMENG;YU SHANGHAI;SUN WEI;SHANGARY SANJEEV KUMAR;SUN DUXIN;ZOU PENG;MCEACHERN DONNA;ZHAO YUJUN |
分类号 |
C07D487/10;A61K31/407;A61K31/454;A61K31/496;A61K31/5377;A61K31/675;A61P1/00;A61P35/04 |
主分类号 |
C07D487/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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