发明名称 PROCESS FOR THE PREPARATION OF CALCOBUTROL
摘要 <p>The invention concerns a process for the preparation of the calcium complex of 0-(2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclodecane-,4,7-triacetic acid, also known as Calcobutrol, starting from the pure gadolinium complex (Gadobutrol). The invention furthermore concerns Calcobutrol with a hitherto unknown level of purity.</p>
申请公布号 WO2011054827(A1) 申请公布日期 2011.05.12
申请号 WO2010EP66655 申请日期 2010.11.02
申请人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;PLATZEK, JOHANNES;TRENTMANN, WILHELM 发明人 PLATZEK, JOHANNES;TRENTMANN, WILHELM
分类号 C07D257/02;A61K49/10 主分类号 C07D257/02
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