| 摘要 |
Anatomical structures such as the musculoskeletal structure of a knee or hip joint, are modeled using a predictive cause-and-effect mathematical model wherein parameters and interactions associated with biological tissues are examined. The model extends over nested small scale parameters (e.g., genetic or cellular) up to macro scale parameters, e.g., body force and motion. The parameter values are populated for a subject or group, and the model is operated iteratively while subjecting the parameters to one or more influences, to project changes over a span of time that encompasses adaptive changes in tissues and also aging and wear. |
