| 摘要 |
Disclosed are oligo- or polysiloxanes, which are characterized by containing at least 3, for example 4-3000, Si atoms in the main chain, and wherein at least one thereof is contained in a moiety of the formula (I) whose open bond of the O atom is linked to another Si atom of the oligo- or polysiloxane main chain, and whose open bond of the Si atom is linked either to another O atom of the oligo- or polysiloxane main chain or to R′1, where R1 and R′1 independently are C1-C10alkyl, R2 and R3 independently are C1-C18alkylene, X is a divalent spacer group selected from O, NR4, N(COR′5), CONR′4, OCONR′4;. Y is selected from OCOR5, NHCOR5, NHR4, COOR5, CONHR4, NR′4R4; R4 is selected from C6-C18 organic residues containing at least one aryl moiety; R′4 is as defined for R4; or is selected from H, C1-C20alkyl, C7-C20phenylalkyl, C4-C12cycloalkyl; R5 is R7—Z; R′5 is as defined for R5; or is selected from H, C1-C20alkyl, C7-C20phenylalkyl, C4-C12cycloalkyl; R7 is C1-C20alkylene, which may be interrupted by phenylene, C4-C12cycloalkylene, O, NR′4; or is unsubstituted or substituted phenylene or C4-C12cycloalkylene; Z is halogen or N+R8R8R10; R8, R9 and R10 independently are selected from C1-C20alkyl, C7-C20phenylalkyl, C4-C12cycloalkyl, unsubstituted or substituted aryl; or 2 of R8, R9 and R10 are linked together to form a quaternized aliphatic, substituted or unsubstituted N-heterocyclic ring of 4-6 carbon atoms such as a piperidine ring; or all of R8, R9 and R10 are linked together to form, together with the nitrogen atom they are bonding to, a substituted or unsubstituted N-heterocyclic ring system of 4-7 carbon atoms. The novel compounds are effective as antimicrobials.
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