发明名称 |
Modulating levels of RNA-binding proteins for the treatment of breast cancer |
摘要 |
The present invention relates to methods of using RNA-binding protein modulating agents to treat of cancer, particularly patients that are susceptible to or diagnosed with estrogen receptor-negative breast cancer, such as methods of inhibiting the growth or metastasis of cancer cells comprising contacting cells with a therapeutically-effective amount of an HuR-modulating agent. The invention also relates to compositions comprising therapeutically-effective amounts of an HuR-modulating agent.
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申请公布号 |
US2011110896(A1) |
申请公布日期 |
2011.05.12 |
申请号 |
US20100924953 |
申请日期 |
2010.10.08 |
申请人 |
THE CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
ATASOY ULUS;GUBIN MATTHEW MICHAEL;CALALUCE ROBERT |
分类号 |
A61K31/713;A61K31/7088;A61K35/76;A61P35/00;A61P35/04;C07H21/00;C07H21/04;C12N5/09;C12N15/63 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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