发明名称 COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION
摘要 Compounds of the general formula (I) and (II) (including formulae (III) to (V)), wherein X=—CH2—, —O—, —S— n=0-10 Y=—NH—, —NHSO2—, —NHSO—, —NHCO—, —S—, —O—, —CH═CH—R1-R7, equal or different can be hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl; may be substituted with one or more alkyl C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; —NR8R9, where R8 e R9, equal or different, represent hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl, may be substituted with one or more C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; —(CH2)n, —COOR10, with n′=0-4 and R3=hydrogen or alkyl C1-C4, and their addition salts with organic and inorganic acids, or alkaline and alkaline earth metal or ammonium ions, with the exclusion of the compounds having the following formulae ((VI) to (IX)).
申请公布号 US2011112184(A1) 申请公布日期 2011.05.12
申请号 US20090991455 申请日期 2009.05.07
申请人 LA PERLA BARBARA;NICOTRA FRANCESCO;BALSARI ANDREA;PALAZZO MARCO;RUMIO CRISTIANO 发明人 LA PERLA BARBARA;NICOTRA FRANCESCO;BALSARI ANDREA;PALAZZO MARCO;RUMIO CRISTIANO
分类号 A61K31/351;A61K31/35;A61P3/10;C07D311/00;C07D315/00 主分类号 A61K31/351
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