| 摘要 |
PROBLEM TO BE SOLVED: To provide a treatment, prevention or diagnosis agent composition for canities and premature canities. SOLUTION: The invention concerns the use of at least one polynucleotide fragment comprising at least 18 consecutive nucleotides wherein the sequence corresponds to all or part of the human chromosome 6 gene selected among the HLAG, NT_007592.445, NT_007592.446, NT_007592.506, and NT_007592.507 genes, or wherein the sequence corresponds to all or part of the human chromosome 3 gene selected among the FREQ, NT_030046.18, NT_030046.17, GTF3C5, CEL, CELL, FS, ABO, BARHL1, DDX31, GTF3C4, and Q96MA6 genes, the use of agents modifyable of the function attached to one of the regions, the use of expression products of one of the regions and the use of agents modifyable of the function of the expression products. COPYRIGHT: (C)2011,JPO&INPIT |
