| 发明名称 |
ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES |
| 摘要 |
The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds. |
| 申请公布号 |
PT2057165(E) |
申请公布日期 |
2011.05.12 |
| 申请号 |
PT20070834863T |
申请日期 |
2007.09.07 |
| 申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;INDUSTRIAL RESEARCH LIMITED |
发明人 |
VERN L. SCHRAMM;KEITH CLINCH;GARY BRIAN EVANS;RICHARD HUBERT FURNEAUX;PETER MICHAEL KELLY;PETER CHARLES TYLER;ANTHONY DAVID WOOLHOUSE;SHIVALI ASHWIN GULAB |
| 分类号 |
C07D487/04;A61K31/519;A61P17/06;A61P31/04;A61P33/02;A61P35/00;A61P37/06 |
主分类号 |
C07D487/04 |
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