发明名称 |
SELECTIVE INHIBITION OF POLYGLUTAMINE PROTEIN EXPRESSION |
摘要 |
The present invention relates to the selective inhibition of protein expression of CAG repeat-related disease proteins such as Huntington using nucleic acid analogs. Peptide nucleic acids and locked nucleic acids are particularly useful analogs. |
申请公布号 |
EP2317847(A1) |
申请公布日期 |
2011.05.11 |
申请号 |
EP20090803468 |
申请日期 |
2009.07.28 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
COREY, DAVID, R.;HU, JIAXIN;MATSUI, MASAYUKI |
分类号 |
A01N43/00;A61K31/70;A61K47/48 |
主分类号 |
A01N43/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|