发明名称 |
STABLE INJECTABLE OIL-IN-WATER DOCETAXEL NANOEMULSION |
摘要 |
<p>The present invention describes Stable injectable oil-in-water Docetaxel nanoemulsion composition having Docetaxel concentrations as high as 20 mg/ml, devoid of hypersensitivity reaction and fluid retention. It employs Synthetic triglycerides, and DSPE PEG-2000, Natural phosphatides, Polyhydric alcohol and Water for injection. In another embodiment lyophilised products with added Cryoprotectants have been described which on reconstitution gives nanoemulsion suitable for parenteral administration.</p> |
申请公布号 |
EP2317978(A2) |
申请公布日期 |
2011.05.11 |
申请号 |
EP20090768245 |
申请日期 |
2009.07.22 |
申请人 |
BHARAT SERUMS AND VACCINES LTD. |
发明人 |
DAFTARY, GAUTAM, VINOD;PAI, SRIKANTH, ANNAPPA;KULKARNI, MANGESH, MANIKRAO |
分类号 |
A61K9/107;A61K9/19;A61K31/337;A61K47/26 |
主分类号 |
A61K9/107 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|