发明名称 |
System and method for the treatment of cancer, including cancers of the central nervous system |
摘要 |
The invention relates to the treatment of cancer, and particularly to the treatment of cancers of the central nervous system, such as glioblastoma multiforme. A dual therapeutic approach is provided, including the administration of a dendritic cell-based cancer vaccine and a regimen of chemotherapy. The two therapies may be administered concurrently with one another and/or with an initial vaccination preceding chemotherapy. In various embodiments, the dendritic cell-based cancer vaccine includes either primed or unprimed dendritic cells; for instance, the dendritic cells may be autologous tumor antigen-presented dendritic cells. The dual therapeutic approach of the instant invention beneficially influences the chemosensitivity of a mammal with cancer.
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申请公布号 |
US7939090(B2) |
申请公布日期 |
2011.05.10 |
申请号 |
US20060575438 |
申请日期 |
2006.04.11 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
WHEELER CHRISTOPHER;DAS ASHA;BLACK KEITH L. |
分类号 |
A61K39/00;A61K45/06;C12N5/02;C12N5/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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